Bryan Quach

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Alcohol use disorder-associated DNA methylation in the nucleus accumbens and dorsolateral prefrontal cortex

Evaluating 17 methods incorporating biological function with GWAS summary statistics to accelerate discovery demonstrates a tradeoff between high sensitivity and high positive predictive value

Trans-ancestry epigenome-wide association meta-analysis of DNA methylation with lifetime cannabis use

Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Multi-omic network analysis identifies key neurobiological pathways in opioid addiction (t121)

Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits

Chromatin architecture in addiction circuitry identifies risk genes and biological mechanisms underlying cigarette smoking and alcohol use traits

Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose

Using omics to understand the adverse effects of cocaine use on HIV outcomes

Strategies for cellular deconvolution in human brain RNA sequencing data

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

Integration of evidence across human and model organism studies: A meeting report

Epigenome-wide analysis uncovers a blood-based DNA methylation biomarker of lifetime cannabis use

Chromatin architecture in addiction circuitry elucidates biological mechanisms underlying cigarette smoking and alcohol use traits

Genome-wide DNA methylation differences in nucleus accumbens of smokers vs. nonsmokers

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation

Correcting nucleotide-specific biases in high-throughput sequencing data

DeFCoM: Analysis and modeling of transcription factor binding sites using a motif-centric genomic footprinter